Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.68 |
| ▸ | TTR | P02766 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.68 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.68 |
| ▸ | PPARG | P37231 | 1/20 | 0.68 |
| ▸ | HTR2B | P41595 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.68 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.68 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.42 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11090319 | 0.94 | PPARA (0.75) | PPARACYP2C9TSHRCYP2C8TTR | |
| SCHEMBL9702591 | 0.91 | PPARA (0.68) | PPARACYP2C9TSHRCYP2C8TTR | |
| SCHEMBL9701998 | 0.88 | PPARA (0.68) | PPARACYP2C9TSHRCYP2C8TTR | |
| SCHEMBL2727802 | 0.87 | PPARA (0.66) | PPARACYP2C9TSHRCYP2C8TTR | |
| SCHEMBL29840766 | 0.85 | PPARA (0.64) | PPARACYP2C9TSHRCYP2C8TTR | |
| SCHEMBL21753575 | 0.85 | PPARA (0.64) | PPARACYP2C9TSHRCYP2C8TTR | |
| SCHEMBL13284589 | 0.85 | PPARA (0.64) | PPARACYP2C9TSHRCYP2C8TTR | |
| SCHEMBL21753581 | 0.85 | PPARA (0.64) | PPARACYP2C9TSHRCYP2C8TTR | |
| SCHEMBL9463720 | 0.85 | PPARA (0.64) | PPARACYP2C9TSHRCYP2C8TTR | |
| SCHEMBL9463457 | 0.82 | PPARA (0.60) | PPARACYP2C9TSHRCYP2C8TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166398-A | Anticholesterol agents or atherosclerosis | WARNER-LAMBERT CO. (US) | 1992-11-24 | — | — | US | disclosed |