Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9332121 | 0.97 | POLB (0.44) | PTGDR2CYP19A1CYP11B1CYP11B2KMT2A | |
| SCHEMBL9701980 | 0.87 | CYP19A1 (0.56) | PTGDR2CYP19A1CYP11B1CYP11B2KMT2A | |
| SCHEMBL29315511 | 0.85 | KDM4E (0.54) | KMT2AMEN1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL8627499 | 0.84 | CYP19A1 (0.55) | PTGDR2CYP19A1CYP11B1CYP11B2KMT2A | |
| SCHEMBL25123541 | 0.82 | KDM4E (0.53) | KMT2AMEN1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL29315515 | 0.82 | KDM4E (0.56) | KMT2AMEN1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7524394 | 0.79 | KDM4E (0.55) | KMT2AMEN1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL29550232 | 0.79 | KDM4E (0.55) | KMT2AMEN1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9332678 | 0.79 | POLB (0.61) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL8631711 | 0.77 | POLB (0.47) | PTGDR2KMT2AMEN1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155793-A | OPTICAL COMPONENT FOR APPLICATIONS IN INTEGRATED OPTICS | THOMSON-CSF (FR) | 1992-10-13 | — | — | US | disclosed |