Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13239564 | 1.00 | LPAR3 (0.44) | LPAR3LPAR2TSHRTP53TDP1 | |
| SCHEMBL9701956 | 0.98 | LPAR3 (0.42) | LPAR3LPAR2TSHRTP53TDP1 | |
| SCHEMBL9700826 | 0.93 | TP53 (0.41) | LPAR3LPAR2TSHRTP53TDP1 | |
| SCHEMBL9700834 | 0.85 | TDP1 (0.44) | LPAR3LPAR2TSHRTP53TDP1 | |
| SCHEMBL2955740 | 0.81 | LPAR3 (0.47) | LPAR3LPAR2TSHRTDP1ALDH1A1 | |
| SCHEMBL9701750 | 0.81 | LPAR3 (0.47) | LPAR3LPAR2TSHRTDP1ALDH1A1 | |
| SCHEMBL8993904 | 0.81 | LPAR3 (0.47) | LPAR3LPAR2TSHRTDP1ALDH1A1 | |
| SCHEMBL1219734 | 0.79 | PPARD (0.47) | LPAR3LPAR2TSHRTDP1ALDH1A1 | |
| SCHEMBL9697474 | 0.79 | LPAR3 (0.46) | LPAR3LPAR2TP53TDP1 | |
| SCHEMBL9697844 | 0.79 | LPAR3 (0.46) | LPAR3LPAR2TP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0478292-A1 | Heterocyclic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-04-01 | — | — | EP | disclosed |