Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 18/20 | 0.54 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.50 |
| ▸ | FLT1 | P17948 | 1/20 | 0.50 |
| ▸ | GRK5 | P34947 | 1/20 | 0.50 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.50 |
| ▸ | CDK8 | P49336 | 1/20 | 0.50 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.50 |
| ▸ | PRKX | P51817 | 1/20 | 0.50 |
| ▸ | JAK3 | P52333 | 1/20 | 0.50 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.50 |
| ▸ | BTK | Q06187 | 1/20 | 0.50 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.50 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11094050 | 0.87 | CHEK1 (0.47) | ESR1CHEK1FYNPDGFRBPIM1 | |
| SCHEMBL11207250 | 0.87 | CNR1 (0.53) | ESR1CHEK1FYNPDGFRBPIM1 | |
| SCHEMBL29690576 | 0.87 | CNR1 (0.53) | ESR1CHEK1FYNPDGFRBPIM1 | |
| SCHEMBL9714771 | 0.85 | CHEK1 (0.50) | ESR1CHEK1FYNPDGFRBPIM1 | |
| SCHEMBL3131837 | 0.83 | ESR1 (0.63) | ESR1CHEK1FYNPDGFRBPIM1 | |
| SCHEMBL11687840 | 0.83 | ESR1 (0.55) | ESR1CHEK1FYNPDGFRBPIM1 | |
| SCHEMBL30567648 | 0.81 | CHEK1 (0.72) | ESR1CHEK1FYNPDGFRBPIM1 | |
| SCHEMBL4582043 | 0.81 | CHEK1 (0.72) | ESR1CHEK1FYNPDGFRBPIM1 | |
| SCHEMBL9702091 | 0.80 | CHEK1 (0.57) | ESR1CHEK1FYNPDGFRBPIM1 | |
| Bisphenol A SCHEMBL9502167 | 0.79 | ESR1 (0.58) | ESR1CHEK1FYNPDGFRBPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110897-A | Food and beverage containers | GENERAL ELECTRIC COMPANY (US) | 1992-05-05 | — | — | US | disclosed |
| EP-0406640-A2 | Thermoplastic polycarbonate compositions having improved oxygen barrier properties | GENERAL ELECTRIC COMPANY (US) | 1991-01-09 | — | — | EP | disclosed |