SCHEMBL9702262

SCHEMBL9702262

COCc1noc(C2=CCCNC2)n1

nearest known ligand 0.66

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 13/20 0.66
CHRM3 P20309 12/20 0.66
CHRM4 P08173 11/20 0.66
CHRM5 P08912 11/20 0.66
CHRM1 P11229 11/20 0.66
HTR2A P28223 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxalic Acid SCHEMBL9704970 0.93 CHRM3 (0.64) CHRM2CHRM3CHRM4CHRM5CHRM1
Oxalic Acid SCHEMBL9704979 0.93 CHRM3 (0.64) CHRM2CHRM3CHRM4CHRM5CHRM1
SCHEMBL9702355 0.80 CHRM2 (1.00) CHRM2CHRM3CHRM4CHRM5CHRM1
Oxalic Acid SCHEMBL10419462 0.77 CHRM2 (0.65) CHRM2CHRM3CHRM4CHRM5CHRM1
Oxalic Acid SCHEMBL10419459 0.77 CHRM2 (0.65) CHRM2CHRM3CHRM4CHRM5CHRM1
SCHEMBL9724619 0.76 CHRM2 (0.59) CHRM2CHRM3CHRM4CHRM5CHRM1
SCHEMBL10518762 0.76 CHRM2 (0.60) CHRM2CHRM3CHRM4CHRM5CHRM1
Oxalic Acid SCHEMBL9704144 0.76 CHRM2 (0.73) CHRM2CHRM3CHRM4CHRM5CHRM1
Oxalic Acid SCHEMBL9704167 0.76 CHRM2 (0.73) CHRM2CHRM3CHRM4CHRM5CHRM1
Hydrochloric Acid SCHEMBL10518564 0.75 CHRM2 (0.58) CHRM2CHRM3CHRM4CHRM5CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0259621-B1 PIPERIDINE COMPOUNDS AND THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 1992-11-25 EP claimed
US-4933353-A ALZHEIMER*S DISEASE A/S FERROSAN (DE) 1990-06-12 US claimed