Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28137912 | 0.80 | RNPEP (0.32) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL10532408 | 0.79 | TP53 (0.33) | TP53 | |
| SCHEMBL427363 | 0.75 | — | — | |
| SCHEMBL11838143 | 0.70 | — | — | |
| SCHEMBL8623503 | 0.69 | TP53 (0.36) | TP53 | |
| SCHEMBL5671706 | 0.69 | TP53 (0.36) | TP53 | |
| SCHEMBL11550778 | 0.69 | — | — | |
| SCHEMBL9125813 | 0.68 | MAPT (0.38) | — | |
| SCHEMBL10428379 | 0.68 | MAPT (0.38) | — | |
| SCHEMBL22598 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230179-B1 | 4-MORPHOLINYL 1H-INDOLE DERIVATIVES, THEIR SALTS, PROCESS AND INTERMEDIATES OF PREPARATION, USE AS THERAPEUTIC AGENTS, COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1992-09-30 | — | — | EP | disclosed |
| EP-0230179-A2 | 4-Morpholinyl 1H-indole derivatives, their salts, process and intermediates of preparation, use as therapeutic agents, compositions containing them | ROUSSEL-UCLAF (FR) | 1987-07-29 | — | — | EP | disclosed |