Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | GFER | P55789 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9703264 | 1.00 | PBRM1 (0.55) | PBRM1KMT2AGFERSMN1; SMN2MEN1 | |
| SCHEMBL9703489 | 1.00 | PBRM1 (0.55) | PBRM1KMT2AGFERSMN1; SMN2MEN1 | |
| SCHEMBL4796534 | 0.81 | HPGD (0.57) | KMT2AGFERSMN1; SMN2MEN1GAA | |
| SCHEMBL4796530 | 0.81 | HPGD (0.57) | KMT2AGFERSMN1; SMN2MEN1GAA | |
| SCHEMBL24127723 | 0.81 | HPGD (0.57) | KMT2AGFERSMN1; SMN2MEN1GAA | |
| SCHEMBL273196 | 0.80 | HPGD (0.64) | KMT2AGFERSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL27961040 | 0.80 | HPGD (0.64) | KMT2AGFERSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL28341134 | 0.78 | HPGD (0.68) | KMT2AGFERSMN1; SMN2GAAALDH1A1 | |
| Water SCHEMBL9518556 | 0.78 | HPGD (0.61) | KMT2AGFERSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL29509920 | 0.76 | GFER (0.57) | KMT2AGFERSMN1; SMN2MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5086051-A | 1H, 3H-pyrrolo[1,2-c]thiazole-7-carboxamide derivatives and pharmaceutical compositions containing them | RHONE-POULENC SANTE (FR) | 1992-02-04 | — | — | US | disclosed |