Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10722870 | 0.80 | MAOB (0.51) | — | |
| SCHEMBL8574266 | 0.79 | HDAC1 (0.59) | — | |
| SCHEMBL10581272 | 0.79 | ESR1 (0.67) | ESR1MEN1LMNANR3C1TP53 | |
| SCHEMBL6264609 | 0.79 | ESR1 (0.67) | ESR1MEN1LMNANR3C1TP53 | |
| SCHEMBL12459964 | 0.76 | HSD17B3 (0.55) | ESR1MEN1LMNANR3C1TP53 | |
| SCHEMBL10583351 | 0.76 | HSD17B3 (0.55) | ESR1MEN1LMNANR3C1TP53 | |
| SCHEMBL10629794 | 0.71 | ESR1 (0.46) | ESR1MEN1LMNANR3C1TP53 | |
| SCHEMBL12459965 | 0.70 | ESR1 (0.46) | ESR1MEN1LMNANR3C1TP53 | |
| Dienestrol SCHEMBL2896848 | 0.67 | ESR1 (1.00) | ESR1MEN1LMNANR3C1TP53 | |
| SCHEMBL14098710 | 0.67 | ESR1 (0.62) | ESR1MEN1LMNANR3C1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120764-A | Administering penicillamine and allenylamines to inhibit crosslinking of collagen | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-06-09 | — | — | US | disclosed |