Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.76 |
| ▸ | ABL1 | P00519 | 1/20 | 0.59 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.59 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.46 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.46 |
| ▸ | NT5E | P21589 | 2/20 | 0.46 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.34 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8003052 | 1.00 | POLB (0.76) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL9242816 | 0.92 | POLB (0.65) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL21465283 | 0.91 | POLB (0.73) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL23211670 | 0.87 | POLB (0.86) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL23211669 | 0.87 | POLB (0.86) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL15146153 | 0.87 | POLB (1.00) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL19662601 | 0.85 | POLB (0.72) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL19662604 | 0.85 | POLB (0.72) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL12404714 | 0.84 | POLB (0.75) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL18844326 | 0.83 | POLB (0.74) | POLBABL1RIN1P2RY6P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992013869-A1 | METHYLENE PHOSPHONATE NUCLEOSIDE ANALOGS AND OLIGONUCLEOTIDE ANALOGS MADE THEREFROM | GILEAD SCIENCES, INC. (US) | 1992-08-20 | — | — | WO | disclosed |