Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 8/20 | 0.66 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.64 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.64 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.52 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.51 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | AHCY | P23526 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31414425 | 0.90 | CYP3A4 (0.71) | CYP3A4FGFR1SLC22A6ADORA2AADORA1 | |
| SCHEMBL15941844 | 0.87 | CYP3A4 (0.72) | CYP3A4FGFR1SLC22A6ADORA2AADORA1 | |
| SCHEMBL10515026 | 0.85 | FGFR1 (0.67) | CYP3A4FGFR1SLC22A6ADORA2AADORA1 | |
| SCHEMBL10876299 | 0.85 | FGFR1 (0.67) | CYP3A4FGFR1SLC22A6ADORA2AADORA1 | |
| SCHEMBL14669191 | 0.85 | CYP3A4 (0.70) | CYP3A4FGFR1SLC22A6ADORA2AADORA1 | |
| SCHEMBL10515307 | 0.85 | CYP3A4 (0.64) | CYP3A4FGFR1SLC22A6ADORA2AADORA1 | |
| SCHEMBL14669069 | 0.85 | CYP3A4 (0.72) | CYP3A4FGFR1SLC22A6ADORA2AADORA1 | |
| SCHEMBL2556627 | 0.85 | CYP3A4 (0.72) | CYP3A4FGFR1SLC22A6ADORA2AADORA1 | |
| SCHEMBL2556635 | 0.85 | CYP3A4 (0.72) | CYP3A4FGFR1SLC22A6ADORA2AADORA1 | |
| SCHEMBL10514709 | 0.84 | CYP3A4 (0.59) | CYP3A4FGFR1SLC22A6ADORA2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0206459-B1 | 9-(PHOSPHONYLMETHOXYALKYL) ADENINES, METHOD FOR THEIR PREPARATION AND THEIR USE | Ceskoslovenska akademie ved (CS) | 1992-07-15 | — | — | EP | disclosed |
| US-4808716-A | VIRICIDES OR CHEMICAL INTERMEDIATES | CESKOSLOVENSKA AKADEMIC VED (CS) | 1989-02-28 | — | — | US | disclosed |
| EP-0206459-A2 | 9-(Phosphonylmethoxyalkyl) adenines, method for their preparation and their use | Ceskoslovenska akademie ved (CS) | 1986-12-30 | — | — | EP | disclosed |