Chloromethane

Chloromethane

SCHEMBL9703019

CCl.COc1ccc(Cl)cc1

nearest known ligand 0.65

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.65
CA2 P00918 2/20 0.65
CA7 P43166 2/20 0.65
CA9 Q16790 2/20 0.65
CA12 O43570 1/20 0.65
CA14 Q9ULX7 1/20 0.65
HPGD P15428 1/20 0.64
ACHE P22303 1/20 0.52
MAPK1 P28482 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
AHR P35869 1/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
ALDH1A1 P00352 1/20 0.50
TSHR P16473 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
LMNA P02545 1/20 0.49
HTT P42858 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2226770 0.97
SCHEMBL154527 0.97
Water SCHEMBL9443323 0.94 CA1 (0.65) CA1CA2CA7CA9CA12
SCHEMBL28525728 0.94 CA1 (0.65) CA1CA2CA7CA9CA12
Water SCHEMBL28888589 0.94 CA1 (0.65) CA1CA2CA7CA9CA12
Iodide SCHEMBL5695908 0.94 CA1 (0.65) CA1CA2CA7CA9CA12
SCHEMBL29069477 0.94 CA1 (0.65) CA1CA2CA7CA9CA12
SCHEMBL4444134 0.94 CA1 (0.65) CA1CA2CA7CA9CA12
Hydrochloric Acid SCHEMBL11293911 0.94 CA1 (0.65) CA1CA2CA7CA9CA12
Ammonia Solution, Strong SCHEMBL4259791 0.94 CA1 (0.65) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992013820-A1 PROCESS FOR THE PREPARATION OF ALKYL-4-HALOPHENYL ETHERS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-08-20 WO disclosed