Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 3/20 | 1.00 |
| ▸ | GRIN3B | O60391 | 3/20 | 1.00 |
| ▸ | GRIA1 | P42261 | 3/20 | 1.00 |
| ▸ | GRIA2 | P42262 | 3/20 | 1.00 |
| ▸ | GRIA3 | P42263 | 3/20 | 1.00 |
| ▸ | GRIA4 | P48058 | 3/20 | 1.00 |
| ▸ | GRIN1 | Q05586 | 3/20 | 1.00 |
| ▸ | GRIN2A | Q12879 | 3/20 | 1.00 |
| ▸ | GRIN2B | Q13224 | 3/20 | 1.00 |
| ▸ | GRIN2C | Q14957 | 3/20 | 1.00 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 1.00 |
| ▸ | GRIK1 | P39086 | 2/20 | 1.00 |
| ▸ | GRIK2 | Q13002 | 2/20 | 1.00 |
| ▸ | GRIK3 | Q13003 | 2/20 | 1.00 |
| ▸ | GRIK4 | Q16099 | 2/20 | 1.00 |
| ▸ | GRIK5 | Q16478 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | LGALS8 | O00214 | 3/20 | 0.50 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.50 |
| ▸ | FLT1 | P17948 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9704862 | 0.91 | GRIN2D (0.83) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL9703907 | 0.90 | GRIN2D (0.82) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL9703699 | 0.89 | GRIN2D (0.80) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL9704089 | 0.89 | GRIN2D (0.80) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL9703971 | 0.89 | GRIN2D (0.80) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL9704092 | 0.87 | GRIN2D (0.78) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL9703491 | 0.87 | GRIN2D (0.78) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL9704196 | 0.87 | GRIN2D (0.78) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL9705016 | 0.86 | GRIN2D (0.76) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL9703928 | 0.86 | GRIN2D (0.75) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011245-A1 | 2-ACYLAMIDO DERIVATIVES OF 3,4-DIHYDRO-3-OXO-QUINOXALINE HAVING PHARMACEUTICAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1992-07-09 | — | — | WO | claimed |
| WO-1992011245-A1 | 2-ACYLAMIDO DERIVATIVES OF 3,4-DIHYDRO-3-OXO-QUINOXALINE HAVING PHARMACEUTICAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1992-07-09 | — | — | WO | disclosed |