SCHEMBL9705010

SCHEMBL9705010

CC(CC=CC(=O)O)(c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 8/20 0.53
ESR2 Q92731 7/20 0.53
ALDH1A1 P00352 3/20 0.53
CYP3A4 P08684 3/20 0.53
TYR P14679 2/20 0.43
AKR1B1 P15121 2/20 0.43
CA12 O43570 1/20 0.43
AKR1B10 O60218 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA3 P07451 1/20 0.43
PKM P14618 1/20 0.43
CA4 P22748 1/20 0.43
CA6 P23280 1/20 0.43
DPP4 P27487 1/20 0.43
CA5A P35218 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43
HCAR2 Q8TDS4 1/20 0.43
CA14 Q9ULX7 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5931186 0.76 ESR1 (0.52) ESR1ESR2ALDH1A1CYP3A4TYR
Bisphenol A SCHEMBL29420718 0.76 ESR1 (0.67) ESR1ESR2ALDH1A1CYP3A4TYR
Bisphenol A SCHEMBL11694690 0.76 ESR1 (0.67) ESR1ESR2ALDH1A1CYP3A4TYR
SCHEMBL3190683 0.75 ESR1 (0.51) ESR1ESR2ALDH1A1CYP3A4TYR
SCHEMBL4235812 0.72 ESR1 (0.67) ESR1ESR2ALDH1A1CYP3A4TYR
SCHEMBL5459169 0.72 ESR1 (0.48) ESR1ESR2ALDH1A1CYP3A4TYR
SCHEMBL3693607 0.70 ESR1 (0.54) ESR1ESR2ALDH1A1CYP3A4TYR
SCHEMBL7522032 0.70 ESR1 (0.47) ESR1ESR2ALDH1A1CYP3A4TYR
Fumaric Acid SCHEMBL11213285 0.70 MAPT (0.73) ESR1ESR2ALDH1A1CYP3A4TYR
Maleic Acid SCHEMBL11213277 0.70 MAPT (0.73) ESR1ESR2ALDH1A1CYP3A4TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0222059-B1 IMPROVED RADIATION-HARDENABLE DILUENTS HENKEL CORPORATION (a Delaware corp.) (US) 1992-07-08 EP claimed