Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 10/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.51 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.51 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.50 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.49 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.49 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9706200 | 0.94 | TYMP (0.59) | TYMPADORA1P2RY12BMPR1BP2RY2 | |
| SCHEMBL8612941 | 0.91 | TYMP (0.52) | TYMPADORA1P2RY12BMPR1B | |
| SCHEMBL8612947 | 0.91 | TYMP (0.52) | TYMPADORA1P2RY12BMPR1B | |
| SCHEMBL8610091 | 0.89 | TYMP (0.52) | TYMPADORA1 | |
| SCHEMBL9705666 | 0.85 | TYMP (0.58) | TYMPADORA1P2RY12P2RY2P2RY1 | |
| SCHEMBL8610332 | 0.85 | TYMP (0.67) | TYMPADORA1 | |
| SCHEMBL8610982 | 0.84 | TYMP (0.83) | TYMPADORA1 | |
| SCHEMBL8610268 | 0.83 | TYMP (0.63) | TYMPADORA1 | |
| SCHEMBL8610799 | 0.83 | TYMP (0.63) | TYMPADORA1 | |
| SCHEMBL9550751 | 0.83 | TYMP (0.69) | TYMPADORA1P2RY12P2RY2P2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011276-A1 | NOVEL SYNTHESIS OF 2'-'UP' FLUORINATED 2''-DEOXY-ARABINOFURANOSYLPURINES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-07-09 | — | — | WO | claimed |
| WO-1992011276-A1 | NOVEL SYNTHESIS OF 2'-'UP' FLUORINATED 2''-DEOXY-ARABINOFURANOSYLPURINES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-07-09 | — | — | WO | disclosed |