Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL10519855 | 0.93 | HSD17B10 (0.51) | NOTUMKMT2AKDM4EMEN1MAPT | |
| SCHEMBL3704956 | 0.89 | NOTUM (0.61) | NOTUMKMT2AMEN1MAPTTMPRSS2 | |
| SCHEMBL29728593 | 0.89 | NOTUM (0.61) | NOTUMKMT2AMEN1MAPTTMPRSS2 | |
| SCHEMBL10962838 | 0.77 | HSD17B3 (0.52) | NOTUMKMT2AKDM4EMEN1MAPT | |
| SCHEMBL29560844 | 0.76 | NOTUM (0.68) | NOTUMKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL546055 | 0.76 | NOTUM (0.68) | NOTUMKMT2AMEN1MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL6651696 | 0.75 | NOTUM (0.66) | NOTUMKMT2AMEN1MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL30061394 | 0.75 | NOTUM (0.66) | NOTUMKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL8667320 | 0.75 | KMT2A (0.60) | KMT2AKDM4EMEN1MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL1075430 | 0.75 | NOTUM (0.66) | NOTUMKMT2AMEN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0192034-B1 | DIBENZAZEPINE DERIVATIVES, THEIR PREPARATION, STARTING MATERIALS FOR THEIR PREPARATION, AND USE OF THE DIBENZAZEPINE DERIVATIVES AS PESTICIDES | CIBA-GEIGY AG (CH) | 1992-07-15 | — | — | EP | claimed |
| EP-0192034-A2 | Dibenzazepine derivatives, their preparation, starting materials for their preparation, and use of the dibenzazepine derivatives as pesticides | CIBA-GEIGY AG (CH) | 1986-08-27 | — | — | EP | claimed |
| EP-0192034-B1 | DIBENZAZEPINE DERIVATIVES, THEIR PREPARATION, STARTING MATERIALS FOR THEIR PREPARATION, AND USE OF THE DIBENZAZEPINE DERIVATIVES AS PESTICIDES | CIBA-GEIGY AG (CH) | 1992-07-15 | — | — | EP | disclosed |
| EP-0368176-A1 | Esters of carboximidic acid, their preparation, and their use as pesticides | CIBA-GEIGY AG (CH) | 1990-05-16 | — | — | EP | disclosed |
| US-4833245-A | CHEMICAL INTERMEDIATES FOR INSECTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1989-05-23 | — | — | US | disclosed |
| US-4766115-A | 5,6-dihydro-6H-dibenz[c,e]azepine-6-(thio)carboximidic acid esters and insecticidal use thereof | HOFFMANN-LA ROCHE INC. (US) | 1988-08-23 | — | — | US | disclosed |
| EP-0192034-A2 | Dibenzazepine derivatives, their preparation, starting materials for their preparation, and use of the dibenzazepine derivatives as pesticides | CIBA-GEIGY AG (CH) | 1986-08-27 | — | — | EP | disclosed |