Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 14/20 | 0.56 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.48 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.48 |
| ▸ | CPA3 | P15088 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29260837 | 0.88 | FOLH1 (0.52) | FOLH1GRM3 | |
| SCHEMBL11381471 | 0.81 | CHRM1 (0.38) | FOLH1 | |
| SCHEMBL25208721 | 0.79 | FOLH1 (0.52) | FOLH1GRM3NAALAD2CPA3 | |
| SCHEMBL7941425 | 0.78 | FOLH1 (0.56) | FOLH1GRM3NAALAD2CPA3 | |
| SCHEMBL108166 | 0.78 | FOLH1 (0.76) | FOLH1GRM3NAALAD2 | |
| SCHEMBL10454283 | 0.77 | FOLH1 (0.54) | FOLH1GRM3NAALAD2 | |
| SCHEMBL13726298 | 0.76 | FOLH1 (0.73) | FOLH1GRM3NAALAD2 | |
| SCHEMBL27996973 | 0.76 | FOLH1 (0.73) | FOLH1GRM3NAALAD2 | |
| SCHEMBL29060942 | 0.76 | FOLH1 (0.73) | FOLH1GRM3NAALAD2 | |
| SCHEMBL11274919 | 0.76 | TET2 (0.44) | FOLH1GRM3NAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207252-B1 | AROMATIC HYDROXY- OR THIOL DERIVATIVES OF CARBONIC-ACID ESTERS AS LIPASE SUBSTRATES | Roche Diagnostics GmbH (DE) | 1992-07-29 | — | — | EP | disclosed |
| EP-0207252-A2 | Aromatic hydroxy- or thiol derivatives of carbonic-acid esters as lipase substrates | Roche Diagnostics GmbH (DE) | 1987-01-07 | — | — | EP | disclosed |