Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Monoethanolamine SCHEMBL3798725 | 0.90 | — | — | |
| Monoethanolamine SCHEMBL446473 | 0.90 | TSHR (0.80) | — | |
| Monoethanolamine SCHEMBL1482117 | 0.90 | — | — | |
| Monoethanolamine SCHEMBL3219813 | 0.90 | — | — | |
| Monoethanolamine SCHEMBL5701520 | 0.90 | TSHR (0.80) | — | |
| Monoethanolamine SCHEMBL1331364 | 0.89 | — | — | |
| Monoethanolamine SCHEMBL1332111 | 0.89 | — | — | |
| Monoethanolamine SCHEMBL14675689 | 0.89 | TSHR (1.00) | — | |
| Monoethanolamine SCHEMBL29663853 | 0.89 | — | — | |
| Monoethanolamine SCHEMBL1644 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103481693-B | Water-based protective coating and its preparation method on solid inkjet printed product | 施乐公司 | 2018-05-11 | — | — | CN | disclosed |
| CN-107304169-A | The method that water-soluble nitrogen-containing compound or its aqueous solution react production product with cyclic ethers | 佳化化学股份有限公司 | 2017-10-31 | — | — | CN | disclosed |
| CN-103772736-A | Nanometer confinement functional material and preparation method and application thereof | NANJING UNIVERSITY OF TECHNOLOGY | 2014-05-07 | — | — | CN | disclosed |
| EP-0228663-B1 | SUBSTRATE FORMULATION IN 2-AMINO-2-METHYL-1-PROPANOL BUFFER FOR ALKALINE PHOSPHATASE ASSAYS | ABBOTT LABORATORIES (US) | 1992-08-12 | — | — | EP | disclosed |
| US-4748115-A | Substrate formulation in 2-amino-2-methyl-1-propanol buffer for alkaline phosphatase assays | ABBOTT LABORATORIES (US) | 1988-05-31 | — | — | US | disclosed |
| EP-0228663-A2 | Substrate formulation in 2-amino-2-methyl-1-propanol buffer for alkaline phosphatase assays | ABBOTT LABORATORIES (US) | 1987-07-15 | — | — | EP | disclosed |
| US-4030995-A | Alkaline phosphatase isoenzyme determination | SIGMA CHEMICAL COMPANY (US) | 1977-06-21 | — | — | US | disclosed |