Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HTR1B | P28222 | 2/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17159543 | 0.93 | HTR1B (0.42) | MEN1POLBKMT2AHTR1BHTR1D | |
| SCHEMBL22416456 | 0.88 | HTR1B (0.42) | MEN1POLBKMT2AHTR1BHTR1D | |
| SCHEMBL9706139 | 0.88 | HTR1B (0.40) | MEN1POLBKMT2AHTR1BCHRM2 | |
| SCHEMBL20394653 | 0.88 | MEN1 (0.50) | MEN1POLBKMT2AKDM4ECHRM2 | |
| Ammonia Solution, Strong SCHEMBL28832288 | 0.86 | MEN1 (0.48) | MEN1POLBKMT2AKDM4ECHRM2 | |
| SCHEMBL9705194 | 0.85 | MEN1 (0.52) | MEN1POLBKMT2AKDM4ECHRM2 | |
| SCHEMBL15003861 | 0.85 | MEN1 (0.52) | MEN1POLBKMT2AKDM4ECHRM2 | |
| SCHEMBL135077 | 0.84 | MEN1 (0.61) | MEN1POLBKMT2AKDM4ECHRM2 | |
| SCHEMBL21126403 | 0.84 | MEN1 (0.50) | MEN1POLBKMT2ATSHR | |
| SCHEMBL10731682 | 0.84 | MEN1 (0.50) | MEN1POLBKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0214852-B1 | PERFLUOROAMINOETHERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-10-28 | — | — | EP | disclosed |
| US-5049670-A | Pour point | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-09-17 | — | — | US | disclosed |
| US-4929725-A | NONFLAMMABLE, HYDRAULIC FLUIDS | MOORE GEORGE G I (US) | 1990-05-29 | — | — | US | disclosed |
| US-4788339-A | HIGH BOILING, LOW POUR POINT; HYDRAULIC FLUIDS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1988-11-29 | — | — | US | disclosed |