Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9706081 | 0.89 | MAPT (0.38) | MEN1KMT2ANR1I2AHRMAPT | |
| SCHEMBL9706132 | 0.88 | MAPT (0.51) | MEN1KMT2ANR1I2AHRMAPT | |
| SCHEMBL9706303 | 0.86 | MAPT (0.50) | MEN1KMT2ANR1I2AHRMAPT | |
| SCHEMBL9706170 | 0.84 | KMT2A (0.60) | MEN1KMT2ANR1I2AHRMAPT | |
| SCHEMBL9706113 | 0.79 | MAPK1 (0.37) | MEN1KMT2ANR1I2AHRMAPT | |
| SCHEMBL9706156 | 0.76 | MAPK1 (0.50) | MEN1KMT2ANR1I2AHRMAPT | |
| SCHEMBL8121238 | 0.75 | MAPT (0.38) | MEN1KMT2ANR1I2AHRMAPT | |
| SCHEMBL9706165 | 0.73 | KMT2A (0.61) | MEN1KMT2ANR1I2AHRMAPT | |
| Dimethylamine SCHEMBL9706158 | 0.73 | MAPT (0.60) | MEN1KMT2ANR1I2AHRMAPT | |
| SCHEMBL1581067 | 0.73 | MAPT (0.57) | MEN1KMT2ANR1I2AHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238459-B1 | SUBSTITUTED INDOLOQUINOXALINES | Lundblad, Leif (SE) | 1992-04-15 | — | — | EP | claimed |
| WO-1987004436-A1 | SUBSTITUTED INDOLOQUINOXALINES | LUNDBLAD, LEIF (SE) | 1987-07-30 | — | — | WO | claimed |