Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 7/20 | 0.60 |
| ▸ | HTR3E | A5X5Y0 | 5/20 | 0.56 |
| ▸ | HTR3B | O95264 | 5/20 | 0.56 |
| ▸ | HTR3A | P46098 | 5/20 | 0.56 |
| ▸ | HTR3D | Q70Z44 | 5/20 | 0.56 |
| ▸ | HTR3C | Q8WXA8 | 5/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3225472 | 0.86 | CHRNA7 (0.78) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL2218010 | 0.86 | CHRNA7 (0.78) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL3216388 | 0.86 | CHRNA7 (0.78) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| Hydrochloric Acid SCHEMBL7278119 | 0.85 | CHRNA7 (0.76) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| Hydrochloric Acid SCHEMBL18704540 | 0.85 | CHRNA7 (0.76) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL372943 | 0.81 | CHRNA7 (0.74) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL3499803 | 0.78 | CHRNA7 (0.74) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL2230266 | 0.78 | CHRNA7 (0.74) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL7381736 | 0.78 | CHRNA7 (0.63) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL4205298 | 0.75 | CHRNA7 (0.71) | CHRNA7HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0190915-B1 | Process for the preparation of 2-alkoxy-N-(1-azabicyclo[2.2.2]octan-3-yl) aminobenzamides | SYNTHELABO (FR) | 1992-10-28 | — | — | EP | claimed |
| US-4870181-A | AMIDATION OF 3-AMINOQUINUCLIDINE SALT | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-09-26 | — | — | US | claimed |