SCHEMBL9706436

SCHEMBL9706436

Fc1cccc(COc2ccccc2)c1F

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 6/20 0.57
PARP15 Q460N3 2/20 0.49
PARP10 Q53GL7 2/20 0.49
PARP14 Q460N5 1/20 0.49
ALKBH1 Q13686 1/20 0.48
KCNH2 Q12809 2/20 0.46
APP P05067 1/20 0.44
HPD P32754 1/20 0.44
NPC1 O15118 1/20 0.43
CASP3 P42574 1/20 0.43
RAB9A P51151 1/20 0.43
SENP8 Q96LD8 1/20 0.43
SENP7 Q9BQF6 1/20 0.43
SENP6 Q9GZR1 1/20 0.43
GRM5 P41594 1/20 0.43
KDM4E B2RXH2 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
IDO1 P14902 1/20 0.42
PTPRC P08575 1/20 0.42
PTPN1 P18031 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17644774 0.86 MAOB (0.68) MAOBPARP15PARP10PARP14HPD
SCHEMBL7025478 0.85 MAOB (0.54) MAOBPARP15PARP10PARP14ALKBH1
Hydrochloric Acid SCHEMBL28551904 0.84 MAOB (0.69) MAOBPARP15PARP10PARP14KCNH2
SCHEMBL17514826 0.84 MAOB (0.49) MAOBPARP15PARP10PARP14ALKBH1
SCHEMBL5391050 0.84 MAOB (0.57) MAOBPARP15PARP10PARP14ALKBH1
SCHEMBL6308598 0.82 MAOB (0.59) MAOBPARP15PARP10PARP14ALKBH1
SCHEMBL4639016 0.81 MAOB (0.54) MAOBPARP15PARP10PARP14ALKBH1
SCHEMBL2560621 0.80 MAOB (0.49) MAOBPARP15PARP10PARP14ALKBH1
SCHEMBL28822452 0.80 MAOB (0.42) MAOBPARP15PARP10PARP14ALKBH1
SCHEMBL1721276 0.79 MAOB (0.55) MAOBPARP15PARP10PARP14ALKBH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0500210-A2 Liquid crystal compounds and compositions SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1992-08-26 EP disclosed