Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | MMP8 | P22894 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6139622 | 0.76 | EPHX1 (0.39) | MMP1MMP8EPHX1KMT2AMAPT | |
| SCHEMBL6755678 | 0.75 | — | — | |
| SCHEMBL91326 | 0.74 | — | — | |
| SCHEMBL7360549 | 0.72 | CYP2D6 (0.48) | CYP2D6CYP2C19MMP1MMP8EPHX1 | |
| SCHEMBL18782865 | 0.72 | CYP2D6 (0.48) | CYP2D6CYP2C19MMP1MMP8EPHX1 | |
| Hydrochloric Acid SCHEMBL30777456 | 0.72 | — | — | |
| SCHEMBL6969767 | 0.71 | CYP2D6 (0.52) | CYP2D6CYP2C19MMP1MMP8EPHX1 | |
| SCHEMBL11692542 | 0.71 | — | — | |
| SCHEMBL8917423 | 0.70 | CYP2D6 (0.56) | CYP2D6CYP2C19MMP1MMP8EPHX1 | |
| SCHEMBL4611409 | 0.70 | SMN1; SMN2 (0.53) | CYP2D6CYP2C19MMP1MMP8EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0196184-B1 | ARYL DERIVATIVES | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-09-16 | — | — | EP | disclosed |