⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL104424 | 0.76 | — | — | |
| SCHEMBL8208318 | 0.76 | — | — | |
| SCHEMBL27823182 | 0.76 | — | — | |
| SCHEMBL2741644 | 0.76 | — | — | |
| SCHEMBL104428 | 0.76 | — | — | |
| SCHEMBL11140099 | 0.76 | USP2 (0.45) | — | |
| SCHEMBL23042488 | 0.74 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL2149050 | 0.73 | — | — | |
| SCHEMBL3684346 | 0.73 | USP2 (0.38) | — | |
| SCHEMBL18898232 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199490-A1 | Penem derivatives | FARMITALIA CARLO ERBA S.r.l. (IT) | 1986-10-29 | — | — | EP | claimed |
| EP-0199490-B1 | PENEM DERIVATIVES | FARMITALIA CARLO ERBA S.r.l. (IT) | 1992-09-23 | — | — | EP | disclosed |
| US-4837215-A | BACTERICIDES; VETERINARY MEDICINE | FARMITALIA CARLO ERBA (IT) | 1989-06-06 | — | — | US | disclosed |