Chlorocresol

Chlorocresol

SCHEMBL9709045

Cc1cc(Cl)ccc1O.Cc1cc(O)ccc1Cl

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 5/20 0.47
HSD17B10 Q99714 4/20 0.47
TSHR P16473 2/20 0.47
CYP3A4 P08684 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
ALDH1A1 P00352 2/20 0.47
ALOX15 P16050 2/20 0.43
CHRM1 P11229 1/20 0.43
MAOA P21397 1/20 0.43
TBXA2R P21731 1/20 0.43
ADRA1A P35348 1/20 0.43
HTR2B P41595 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
TP53 P04637 1/20 0.42
ESR1 P03372 3/20 0.41
HSD17B1 P14061 1/20 0.41
HSD17B2 P37059 1/20 0.41
TLR8 Q9NR97 1/20 0.40
HPGD P15428 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorocresol SCHEMBL27317750 0.96 ESR2 (0.45) ESR2HSD17B10TSHRCYP3A4TDP1
Chlorocresol SCHEMBL10688541 0.84 HSD17B10 (0.50) ESR2HSD17B10TSHRCYP3A4TDP1
Chlorocresol SCHEMBL29377724 0.84
Chlorocresol SCHEMBL6552674 0.84 HSD17B10 (0.59) ESR2HSD17B10CYP3A4ALOX15CHRM1
SCHEMBL171059 0.84
Chlorocresol SCHEMBL12344 0.84
SCHEMBL30991479 0.82 ESR2 (0.59) ESR2HSD17B10TSHRCYP3A4TDP1
Chlorocresol SCHEMBL1712039 0.82 HSD17B10 (0.56) ESR2HSD17B10CYP3A4ALOX15CHRM1
Chlorocresol SCHEMBL29353909 0.82 HSD17B10 (0.56) ESR2HSD17B10CYP3A4ALOX15CHRM1
Chlorocresol SCHEMBL1712038 0.82 HSD17B10 (0.56) ESR2HSD17B10CYP3A4ALOX15CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1346262-A Antimicrobial wipes providing improved immediate germ reduction PROCTER & GAMBER (US) 2002-04-24 CN disclosed
CN-1346264-A Antimicrobial wipes PROCTER & GAMBLE (US) 2002-04-24 CN disclosed
CN-1265581-A Mild, rinse-off antimicrobial liquid cleansing compositions containing salicylic acid PROCTER & GAMBLE (US) 2000-09-06 CN disclosed
CN-1264293-A Liquid anitmicrobial clansing compositions which provide residual benefit versus gram negative bacterial PROCTER & GAMBLE (US) 2000-08-23 CN disclosed
CN-1264294-A Liquid antimicrobial cleansing compositions PROCTER & GAMBLE (US) 2000-08-23 CN disclosed
CN-1263459-A Mild antimicrobial wipes PROCTER & GAMBLE (US) 2000-08-16 CN disclosed
WO-1992010994-A1 ORAL COMPOSITIONS EFFECTIVE AGAINST PLAQUE AND GINGIVITIS THE PROCTER & GAMBLE COMPANY (US) 1992-07-09 WO disclosed