Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.56 |
| ▸ | ACE | P12821 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.46 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17612824 | 0.85 | MME (0.58) | MMEACEMEN1KMT2AALDH1A1 | |
| SCHEMBL11879432 | 0.83 | MEN1 (0.54) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL21498198 | 0.81 | MME (0.54) | MMEACEMEN1KMT2AALDH1A1 | |
| SCHEMBL2844155 | 0.79 | MEN1 (0.52) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL18456226 | 0.79 | MME (0.63) | MMEACEMEN1KMT2AALDH1A1 | |
| SCHEMBL12205972 | 0.79 | MME (0.63) | MMEACEMEN1KMT2AALDH1A1 | |
| SCHEMBL4151615 | 0.79 | MME (0.63) | MMEACEMEN1KMT2AALDH1A1 | |
| SCHEMBL8027661 | 0.79 | MME (0.63) | MMEACEMEN1KMT2AALDH1A1 | |
| SCHEMBL9293872 | 0.78 | MEN1 (0.58) | MEN1KMT2AMAPTNPC1POLB | |
| SCHEMBL9293602 | 0.78 | MEN1 (0.58) | MEN1KMT2AMAPTNPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992016233-A1 | PHARMACEUTICAL COMBINATION FOR THE TREATMENT OF PROSTATIC CANCER CONTAINING A 5 ALPHA REDUCTASE INHIBITOR AND AN ANTIANDROGEN | MERCK & CO., INC. (US) | 1992-10-01 | — | — | WO | disclosed |