Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR17 | Q13304 | 1/20 | 0.71 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709067 | 1.00 | GPR17 (0.71) | GPR17GRIN1MEN1KMT2AKDM4E | |
| Gavestinel SCHEMBL1995818 | 0.84 | GPR17 (0.98) | GPR17GRIN1MEN1KMT2AKDM4E | |
| Gavestinel SCHEMBL678632 | 0.83 | GPR17 (1.00) | GPR17GRIN1MEN1KMT2AKDM4E | |
| Gavestinel SCHEMBL30184856 | 0.83 | GPR17 (1.00) | GPR17GRIN1MEN1KMT2AKDM4E | |
| Gavestinel SCHEMBL1721070 | 0.83 | GPR17 (1.00) | GPR17GRIN1MEN1KMT2AKDM4E | |
| Gavestinel SCHEMBL1995813 | 0.82 | GPR17 (0.98) | GPR17GRIN1MEN1KMT2AKDM4E | |
| Gavestinel SCHEMBL1995817 | 0.82 | GPR17 (0.98) | GPR17GRIN1MEN1KMT2AKDM4E | |
| SCHEMBL9433248 | 0.80 | GPR17 (0.71) | GPR17GRIN1MEN1KMT2AKDM4E | |
| SCHEMBL9433255 | 0.80 | GPR17 (0.71) | GPR17GRIN1MEN1KMT2AKDM4E | |
| SCHEMBL9432740 | 0.80 | GPR17 (0.70) | GPR17MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992016205-A2 | NOVEL DERIVATIVES OF 2-CARBOXYNDOLES HAVING PHARMACEUTICAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1992-10-01 | — | — | WO | claimed |