Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.70 |
| ▸ | TOP1 | P11387 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NT5E | P21589 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL179004 | 0.85 | TOP1 (0.83) | PKMTOP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL30397789 | 0.82 | MEN1 (1.00) | PKMKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL29013036 | 0.82 | MEN1 (1.00) | PKMKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL2605619 | 0.81 | TOP1 (0.67) | PKMTOP1ALDH1A1RAB9ANPC1 | |
| SCHEMBL13238567 | 0.80 | TOP1 (0.74) | PKMTOP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL13947128 | 0.77 | KMT2A (0.79) | PKMKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL11284511 | 0.77 | TOP1 (0.67) | PKMTOP1ALDH1A1RAB9ANPC1 | |
| SCHEMBL13175761 | 0.76 | KMT2A (0.77) | PKMKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL108244 | 0.76 | TOP1 (0.68) | PKMTOP1KMT2AMEN1RAB9A | |
| SCHEMBL27672853 | 0.76 | TOP1 (0.66) | PKMTOP1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0515684-A1 | INHIBITOR OF DENATURED LDL FORMATION | Chugai Seiyaku Kabushiki Kaisha (JP) | 1992-12-02 | — | — | EP | disclosed |