Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | GLRA3 | O75311 | 2/20 | 0.34 |
| ▸ | SQLE | Q14534 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | SNCA | P37840 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709473 | 1.00 | TSHR (0.49) | TSHRPTPN1KDM1AGLRA3SQLE | |
| SCHEMBL9017101 | 0.89 | PTPN1 (0.59) | TSHRPTPN1KDM1AKMT2APTGS1 | |
| SCHEMBL9017099 | 0.89 | PTPN1 (0.59) | TSHRPTPN1KDM1AKMT2APTGS1 | |
| SCHEMBL10922177 | 0.88 | TSHR (0.59) | TSHRPTPN1KDM1ASQLEKMT2A | |
| SCHEMBL10926749 | 0.88 | TSHR (0.59) | TSHRPTPN1KDM1ASQLEKMT2A | |
| SCHEMBL19638663 | 0.87 | TSHR (0.59) | TSHRKDM1ASQLEKMT2A | |
| SCHEMBL19638662 | 0.87 | TSHR (0.59) | TSHRKDM1ASQLEKMT2A | |
| SCHEMBL9017161 | 0.85 | KDM1A (0.55) | TSHRPTPN1KDM1ASQLEKMT2A | |
| SCHEMBL9017166 | 0.85 | KDM1A (0.55) | TSHRPTPN1KDM1ASQLEKMT2A | |
| SCHEMBL9020038 | 0.84 | KDM1A (0.58) | TSHRPTPN1KDM1ASQLEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175346-A | Catalyst mixture of cuprous chloride and quaternary ammonium salt | RHONE-POULENC SANTE (FR) | 1992-12-29 | — | — | US | disclosed |