Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA4 | P43681 | 2/20 | 0.37 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709847 | 1.00 | CHRNA4 (0.37) | CHRNA4RAPGEF3RAPGEF4RAB9APOLB | |
| SCHEMBL9709795 | 0.83 | CHRNA4 (0.38) | CHRNA4RAPGEF3RAPGEF4RAB9APOLB | |
| SCHEMBL9709792 | 0.83 | CHRNA4 (0.38) | CHRNA4RAPGEF3RAPGEF4RAB9APOLB | |
| SCHEMBL9710162 | 0.80 | CHRNA4 (0.35) | CHRNA4RAPGEF3RAPGEF4RAB9APOLB | |
| SCHEMBL28329086 | 0.78 | CHRNA4 (0.38) | CHRNA4RAPGEF3RAPGEF4RAB9APOLB | |
| Propene SCHEMBL28120183 | 0.77 | CHRNA4 (0.37) | CHRNA4RAPGEF3RAPGEF4RAB9APOLB | |
| Benzene SCHEMBL28148287 | 0.73 | KDM4E (0.46) | CHRNA4RAPGEF3RAPGEF4POLBALDH1A1 | |
| SCHEMBL27510675 | 0.72 | CHRNA4 (0.39) | CHRNA4RAPGEF3RAPGEF4RAB9APOLB | |
| SCHEMBL28273457 | 0.72 | CHRNA4 (0.44) | CHRNA4RAPGEF3RAPGEF4RAB9APOLB | |
| SCHEMBL30172890 | 0.72 | CA12 (0.46) | CHRNA4RAPGEF3RAPGEF4CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992020689-A1 | ANTIBACTERIAL PENEM DERIVATIVES | SMITHKLINE BEECHAM P.L.C. (GB) | 1992-11-26 | — | — | WO | disclosed |