Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 3/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7431300 | 1.00 | EPHX2 (0.46) | EPHX2CYP2C9CYP2C19HRH2HRH4 | |
| SCHEMBL9866144 | 0.95 | EPHX2 (0.43) | EPHX2CYP2C9CYP2C19HRH2HRH4 | |
| SCHEMBL9866130 | 0.93 | EPHX2 (0.41) | EPHX2CYP2C9CYP2C19HRH2HRH4 | |
| SCHEMBL9866135 | 0.93 | EPHX2 (0.41) | EPHX2CYP2C9CYP2C19HRH2HRH4 | |
| SCHEMBL9865305 | 0.93 | NPY1R (0.41) | — | |
| SCHEMBL7431296 | 0.92 | EPHX2 (0.41) | EPHX2CYP2C9CYP2C19HRH2 | |
| SCHEMBL7431291 | 0.92 | EPHX2 (0.41) | EPHX2CYP2C9CYP2C19HRH2 | |
| SCHEMBL11080978 | 0.89 | HRH2 (0.47) | HRH2HRH4 | |
| SCHEMBL9866078 | 0.89 | EPHX2 (0.39) | EPHX2 | |
| SCHEMBL7311277 | 0.87 | CNR1 (0.38) | EPHX2HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992022295-A1 | USE OF GUANIDINE DERIVATIVES IN THE PREPARATION OF A DRUG FOR THE TREATMENT OF SEPSIS AND SEPSIS-LIKE CONDITIONS AND SEPTIC SHOCK | NEUGEBAUER EDMUND (DE) | 1992-12-23 | — | — | WO | disclosed |