Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.73 |
| ▸ | TSHR | P16473 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | MMP12 | P39900 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CPA3 | P15088 | 1/20 | 0.41 |
| ▸ | GRM8 | O00222 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9710227 | 1.00 | CYP1A2 (0.73) | CYP1A2TSHRALDH1A1MMP2MMP9 | |
| SCHEMBL4726270 | 0.85 | CYP1A2 (0.68) | CYP1A2TSHRALDH1A1GRM8GRM4 | |
| SCHEMBL4726276 | 0.85 | CYP1A2 (0.68) | CYP1A2TSHRALDH1A1GRM8GRM4 | |
| SCHEMBL7263695 | 0.84 | CYP1A2 (1.00) | CYP1A2TSHRALDH1A1MAPTMEN1 | |
| SCHEMBL7263686 | 0.84 | CYP1A2 (1.00) | CYP1A2TSHRALDH1A1MAPTMEN1 | |
| SCHEMBL11126167 | 0.84 | CYP1A2 (0.67) | CYP1A2TSHRALDH1A1GAARAB9A | |
| SCHEMBL19302979 | 0.83 | CYP1A2 (0.57) | CYP1A2TSHRALDH1A1MAPTHPGD | |
| SCHEMBL9479735 | 0.83 | CYP1A2 (0.74) | CYP1A2TSHRALDH1A1MAPTGRM8 | |
| SCHEMBL3969391 | 0.82 | CYP1A2 (0.65) | CYP1A2TSHRALDH1A1HPGDGRM8 | |
| SCHEMBL3969388 | 0.82 | CYP1A2 (0.65) | CYP1A2TSHRALDH1A1HPGDGRM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992021778-A1 | ASSAYS EMPLOYING ANCHIMERIC ASSISTANCE CLEAVAGE | LIFE TECHNOLOGIES, INC. (US) | 1992-12-10 | — | — | WO | disclosed |