Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 11/20 | 0.62 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.44 |
| ▸ | TK2 | O00142 | 1/20 | 0.44 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.44 |
| ▸ | TK1 | P04183 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15974161 | 1.00 | TYMP (0.62) | TYMPP2RY6TK2P2RY14TK1 | |
| SCHEMBL13714472 | 1.00 | TYMP (0.62) | TYMPP2RY6TK2P2RY14TK1 | |
| SCHEMBL3069438 | 1.00 | TYMP (0.62) | TYMPP2RY6TK2P2RY14TK1 | |
| SCHEMBL6246850 | 1.00 | TYMP (0.62) | TYMPP2RY6TK2P2RY14TK1 | |
| SCHEMBL13205014 | 1.00 | TYMP (0.62) | TYMPP2RY6TK2P2RY14TK1 | |
| SCHEMBL3069436 | 1.00 | TYMP (0.62) | TYMPP2RY6TK2P2RY14TK1 | |
| SCHEMBL5953147 | 0.94 | TYMP (0.57) | TYMPTK2TK1 | |
| SCHEMBL8535403 | 0.94 | TYMP (0.57) | TYMPTK2TK1 | |
| SCHEMBL8535399 | 0.94 | TYMP (0.57) | TYMPTK2TK1 | |
| SCHEMBL4626083 | 0.94 | TYMP (0.57) | TYMPTK2TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0188400-B1 | OLIGOPEPTIDES, INTERMEDIATES AND PROCESS FOR THEIR PREPARATION | CIBA-GEIGY AG (CH) | 1992-07-08 | — | — | EP | disclosed |
| EP-0168342-B1 | PROCESS FOR THE PREPARATION OF THROMBIN INHIBITORS | CIBA-GEIGY AG (CH) | 1991-07-03 | — | — | EP | disclosed |
| EP-0146785-B1 | PROCESS FOR THE PREPARATION OF PROTEASE INHIBITORS | CIBA-GEIGY AG (CH) | 1990-02-07 | — | — | EP | disclosed |
| EP-0188400-A2 | Oligopeptides, intermediates and process for their preparation | CIBA-GEIGY AG (CH) | 1986-07-23 | — | — | EP | disclosed |
| EP-0168342-A1 | Process for the preparation of thrombin inhibitors | CIBA-GEIGY AG (CH) | 1986-01-15 | — | — | EP | disclosed |
| EP-0146785-A1 | Process for the preparation of protease inhibitors | CIBA-GEIGY AG (CH) | 1985-07-03 | — | — | EP | disclosed |