Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Ammonia Solution, Strong. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL16235833 | 1.00 | — | — | |
| Ammonia Solution, Strong SCHEMBL27900460 | 0.87 | — | — | |
| Lithium Ion SCHEMBL3478336 | 0.87 | — | — | |
| Hydrogen Sulfide SCHEMBL27468970 | 0.75 | — | — | |
| Ammonia Solution, Strong SCHEMBL2253277 | 0.75 | — | — | |
| Water SCHEMBL28036631 | 0.75 | — | — | |
| Lithium Ion SCHEMBL5537470 | 0.75 | — | — | |
| Ammonia Solution, Strong SCHEMBL16931525 | 0.75 | — | — | |
| Lithium Ion SCHEMBL11125103 | 0.75 | — | — | |
| Ammonia Solution, Strong SCHEMBL8341599 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105379002-A | Active lithium reservoir for lithium ion batteries | Rockwood Lithium GmbH | 2016-03-02 | — | — | CN | claimed |
| WO-2008078970-A1 | IN SITU PREPARATION OF SUBSTRATES WITH DI SPERSED GOLD NANOPARTICLES | DAEGU GYEONGBUK INSTITUTE OF SCIENCE & TECHNOLOGY (KR) | 2008-07-03 | — | — | WO | claimed |
| US-12263163-B2 | Crystalline succinate salt of 6-(6-aminopyrazin-2-yl)-n-(4-(4-(oxetan-3-yl)piperazin-1-yl)phenyl)imidazo[1,2-a]pyrazin-8-amine as a Syk inhibitor | Kronos Bio, Inc. (US) | 2025-04-01 | — | — | US | disclosed |
| US-20240294707-A1 | COMPOUND, COMPOSITION, SURFACE TREATMENT AGENT, COATING LIQUID, ARTICLE, AND METHOD FOR PRODUCING ARTICLE | AGC Inc. (JP) | 2024-09-05 | — | — | US | disclosed |
| EP-4424745-A1 | COMPOUND, COMPOSITION, SURFACE TREATMENT AGENT, COATING LIQUID, ARTICLE, AND METHOD FOR MANUFACTURING ARTICLE | AGC INC. (JP) | 2024-09-04 | — | — | EP | disclosed |
| CN-111933920-B | Active lithium reservoir for lithium ion battery | 雅宝德国有限责任公司 | 2023-09-29 | — | — | CN | disclosed |
| EP-3152210-B1 | TANK-BINDING KINASE INHIBITOR COMPOUNDS | GILEAD SCIENCES INC (US) | 2023-07-05 | — | — | EP | disclosed |
| US-20230158023-A1 | CRYSTALLINE SUCCINATE SALT OF 6-(6-AMINOPYRAZIN-2-YL)-N-(4-(4-(OXETAN-3-YL)PIPERAZIN-1-YL)PHENYL)IMIDAZO[1,2-a]PYRAZIN-8-AMINE | GILEAD SCIENCES, INC. | 2023-05-25 | — | — | US | disclosed |
| US-11517570-B2 | Crystalline succinate salt of 6-(6-aminopyrazin-2-yl)-n-(4-(4-(oxetan-3-yl)piperazin-1-yl)phenyl)imidazo[1,2-a]pyrazin-8-amine | Kronos Bio, Inc. (US) | 2022-12-06 | — | — | US | disclosed |
| CN-113135554-A | Preparation method of lithium bis (fluorosulfonyl) imide | 湖南福邦新材料有限公司 | 2021-07-20 | — | — | CN | disclosed |
| EP-3342773-B9 | SYK INHIBITORS | KRONOS BIO INC (US) | 2021-06-09 | — | — | EP | disclosed |
| EP-0882718-B1 | BENZIMIDAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 2005-08-31 | — | — | EP | disclosed |
| US-6352985-B1 | CARDIOVASCULAR DISORDERS OR GASTROINTESTINAL DISORDERS, DIABETES (TYPE II DIABETES), DIABETIC COMPLICATIONS METHOD FOR LOWERING THE BLOOD SUGAR LEVEL OF A PATIENT, | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-05 | — | — | US | disclosed |
| US-6166219-A | Benzimidazole derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-12-26 | — | — | US | disclosed |
| EP-0882718-A1 | BENZIMIDAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-12-09 | — | — | EP | disclosed |
| EP-0282068-B1 | Nonaqueous secondary battery | SHOWA DENKO KK (JP) | 1997-06-11 | — | — | EP | disclosed |
| US-4803138-A | POLYANILINE ANODE | SHOWA DENKO K.K. & HITACHI, LTD. (JP) | 1989-02-07 | — | — | US | disclosed |
| EP-0282068-A2 | Nonaqueous secondary battery | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1988-09-14 | — | — | EP | disclosed |
| US-4166174-A | ANALGESICS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1979-08-28 | — | — | US | disclosed |
| US-3966748-A | NEUROLEPTIC, ANALGESIC | AMERICAN CYANAMID COMPANY (US) | 1976-06-29 | — | — | US | disclosed |