Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 7/20 | 0.41 |
| ▸ | GBA2 | Q9HCG7 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NGLY1 | Q96IV0 | 1/20 | 0.33 |
| ▸ | GANAB | Q14697 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7887115 | 1.00 | GBA1 (0.41) | GBA1GBA2GAAMEN1CYP1A2 | |
| SCHEMBL7888503 | 1.00 | GBA1 (0.41) | GBA1GBA2GAAMEN1CYP1A2 | |
| SCHEMBL7893120 | 1.00 | GBA1 (0.41) | GBA1GBA2GAAMEN1CYP1A2 | |
| SCHEMBL7881588 | 1.00 | GBA1 (0.41) | GBA1GBA2GAAMEN1CYP1A2 | |
| SCHEMBL1986413 | 0.83 | — | — | |
| SCHEMBL8502927 | 0.83 | — | — | |
| SCHEMBL22776054 | 0.75 | GBA1 (0.39) | GBA1GBA2GAAMEN1CYP1A2 | |
| SCHEMBL6251355 | 0.72 | — | — | |
| SCHEMBL2878271 | 0.72 | — | — | |
| SCHEMBL24547750 | 0.72 | GBA1 (0.62) | GBA1GBA2GAAMGAMTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992021657-A1 | OMEGA-DEOXY-AZASUGARS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1992-12-10 | — | — | WO | disclosed |