Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 13/20 | 0.52 |
| ▸ | CNR1 | P21554 | 12/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7174292 | 0.98 | CNR2 (0.54) | CNR2CNR1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL14840318 | 0.98 | CNR2 (0.54) | CNR2CNR1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL25007218 | 0.98 | CNR2 (0.54) | CNR2CNR1CYP1A2CYP2C19CYP2C9 | |
| Hydrochloric Acid SCHEMBL28440141 | 0.97 | CNR2 (0.52) | CNR2CNR1CYP1A2CYP2C19CYP2C9 | |
| Water SCHEMBL7549510 | 0.97 | CNR2 (0.52) | CNR2CNR1CYP1A2CYP2C19CYP2C9 | |
| Hydrochloric Acid SCHEMBL9420750 | 0.97 | CNR2 (0.52) | CNR2CNR1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL11445241 | 0.85 | CNR2 (0.46) | CNR2CNR1 | |
| SCHEMBL22877802 | 0.84 | CNR2 (0.47) | CNR2CNR1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL6470377 | 0.83 | CNR1 (0.38) | CNR2CNR1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL11216774 | 0.83 | CNR2 (0.43) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992017614-A1 | COPPER ION FLOTATION WITH CATIONIC REAGENTS | THE BROKEN HILL PROPRIETARY COMPANY LIMITED (AU) | 1992-10-15 | — | — | WO | claimed |
| WO-1990012119-A1 | ION FLOTATION WITH QUATERNARY AMMONIUM CATIONIC SURFACTANTS | THE BROKEN HILL PROPRIETARY COMPANY LIMITED (AU) | 1990-10-18 | — | — | WO | claimed |
| WO-1992020826-A1 | ION FLOTATION OF PLATINUM IONS | THE BROKEN HILL PROPRIETARY COMPANY LIMITED (AU) | 1992-11-26 | — | — | WO | disclosed |
| WO-1992017614-A1 | COPPER ION FLOTATION WITH CATIONIC REAGENTS | THE BROKEN HILL PROPRIETARY COMPANY LIMITED (AU) | 1992-10-15 | — | — | WO | disclosed |