SCHEMBL9711311

SCHEMBL9711311

COc1cc(OC)nc(NC(=O)NS(=O)(=O)Cc2ccccc2C(=O)O)n1.COc1cc(OC)nc(NCC(=O)NS(=O)(=O)Cc2ccccc2C(=O)O)n1

nearest known ligand 0.73

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.47
TP53 P04637 1/20 0.47
GLA P06280 1/20 0.47
GAA P10253 1/20 0.44
KMT2A Q03164 2/20 0.39
CDK1 P06493 1/20 0.38
CYP1A2 P05177 1/20 0.37
ADRB2 P07550 1/20 0.36
HDAC1 Q13547 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.35
MTNR1A P48039 1/20 0.35
MTNR1B P49286 1/20 0.35
HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bensulfuron Methyl SCHEMBL9451055 0.97 MAPT (0.45) MAPTTP53GLAGAAKMT2A
SCHEMBL20834 0.92 MAPT (0.51) MAPTTP53GLAGAAKMT2A
SCHEMBL29386841 0.92 MAPT (0.51) MAPTTP53GLAGAAKMT2A
Bensulfuron Methyl SCHEMBL15019924 0.89 MAPT (0.48) MAPTTP53GLAGAAKMT2A
SCHEMBL10967827 0.86 SMN1; SMN2 (0.50) MAPTTP53GLAGAAKMT2A
SCHEMBL8936659 0.86 MAPT (0.45) MAPTTP53GLAGAAKMT2A
Bensulfuron Methyl SCHEMBL6382944 0.85 GAA (0.51) MAPTTP53GLAGAAKMT2A
Bensulfuron Methyl SCHEMBL29368260 0.85 GAA (0.51) MAPTTP53GLAGAAKMT2A
Bensulfuron Methyl SCHEMBL55028 0.85 GAA (0.51) MAPTTP53GLAGAAKMT2A
Bensulfuron Methyl SCHEMBL27491070 0.85 GAA (0.51) MAPTTP53GLAGAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992020684-A1 HERBICIDAL OXATRICYCLIC ETHERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-11-26 WO disclosed
WO-1992013861-A1 HERBICIDAL BICYCLIC ETHERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-08-20 WO disclosed