Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 19/20 | 0.59 |
| ▸ | CYSLTR1 | Q9Y271 | 19/20 | 0.59 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711409 | 0.92 | CYSLTR2 (0.67) | CYSLTR2CYSLTR1CTSD | |
| SCHEMBL9711393 | 0.89 | CYSLTR1 (0.59) | CYSLTR2CYSLTR1CTSD | |
| SCHEMBL9177390 | 0.88 | CYSLTR2 (0.69) | CYSLTR2CYSLTR1CTSD | |
| SCHEMBL9506508 | 0.87 | CYSLTR2 (0.68) | CYSLTR2CYSLTR1CTSD | |
| SCHEMBL9506488 | 0.87 | CYSLTR2 (0.68) | CYSLTR2CYSLTR1CTSD | |
| SCHEMBL9711392 | 0.86 | CYSLTR2 (0.56) | CYSLTR2CYSLTR1CTSD | |
| SCHEMBL9179953 | 0.85 | CYSLTR2 (0.61) | CYSLTR2CYSLTR1CTSD | |
| SCHEMBL9711396 | 0.85 | CYSLTR2 (0.66) | CYSLTR2CYSLTR1CTSD | |
| SCHEMBL481224 | 0.85 | CYSLTR1 (0.59) | CYSLTR2CYSLTR1CTSD | |
| SCHEMBL9177556 | 0.82 | CYSLTR2 (0.61) | CYSLTR2CYSLTR1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288189-B1 | IMPROVEMENTS IN OR RELATING TO LEUKOTRIENE ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1992-11-11 | — | — | EP | claimed |
| US-4853398-A | ANTIALLERGENS | ELI LILLY AND COMPANY (US) | 1989-08-01 | — | — | US | claimed |
| EP-0288189-A1 | Improvements in or relating to leukotriene antagonists | ELI LILLY AND COMPANY (US) | 1988-10-26 | — | — | EP | claimed |
| EP-0288189-B1 | IMPROVEMENTS IN OR RELATING TO LEUKOTRIENE ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1992-11-11 | — | — | EP | disclosed |
| US-4853398-A | ANTIALLERGENS | ELI LILLY AND COMPANY (US) | 1989-08-01 | — | — | US | disclosed |
| EP-0288189-A1 | Improvements in or relating to leukotriene antagonists | ELI LILLY AND COMPANY (US) | 1988-10-26 | — | — | EP | disclosed |