Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | BRAF | P15056 | 5/20 | 0.38 |
| ▸ | RAF1 | P04049 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9712995 | 0.89 | CYP1A2 (0.47) | ALDH1A1GAABRAFRAF1MAPT | |
| SCHEMBL9712643 | 0.82 | BRAF (0.51) | ALDH1A1BRAFRAF1MAPTSMN1; SMN2 | |
| SCHEMBL9712713 | 0.81 | BRAF (0.40) | ALDH1A1BRAFRAF1MAPTSMN1; SMN2 | |
| SCHEMBL9713900 | 0.80 | MAPK14 (0.50) | ALDH1A1BRAFRAF1MAPTSMN1; SMN2 | |
| SCHEMBL9712698 | 0.80 | BRAF (0.41) | ALDH1A1BRAFRAF1MAPTSMN1; SMN2 | |
| SCHEMBL9712694 | 0.77 | BRAF (0.39) | BRAFRAF1MAPTSMN1; SMN2TP53 | |
| SCHEMBL9712627 | 0.75 | CYP1A2 (0.38) | BRAFRAF1MAPTSMN1; SMN2TP53 | |
| SCHEMBL9713420 | 0.75 | CYP1A2 (0.38) | BRAFRAF1MAPTSMN1; SMN2TP53 | |
| SCHEMBL9712919 | 0.75 | CNR2 (0.42) | BRAFRAF1MAPTTP53CYP1A2 | |
| SCHEMBL9713099 | 0.74 | CYP1A2 (0.49) | ALDH1A1GAABRAFRAF1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5086184-A | Herbicides | DOWELANCO (US) | 1992-02-04 | — | — | US | disclosed |
| US-4943634-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1990-07-24 | — | — | US | disclosed |
| US-4801718-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1989-01-31 | — | — | US | disclosed |
| US-4636243-A | HERBICIDES ISOXAZOLES | ELI LILLY AND COMPANY (US) | 1987-01-13 | — | — | US | disclosed |
| US-4515625-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1985-05-07 | — | — | US | disclosed |
| US-4416683-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1983-11-22 | — | — | US | disclosed |