Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.49 |
| ▸ | SNCA | P37840 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713020 | 1.00 | PLK1 (0.52) | PLK1MEN1RAB9AKMT2ANPC1 | |
| SCHEMBL9713103 | 0.91 | NR1H4 (0.52) | PLK1MEN1RAB9AKMT2ANPC1 | |
| SCHEMBL9713108 | 0.91 | NR1H4 (0.52) | PLK1MEN1RAB9AKMT2ANPC1 | |
| SCHEMBL29608536 | 0.83 | SMN1; SMN2 (0.53) | RAB9AKMT2ANPC1SMN1; SMN2SNCA | |
| SCHEMBL9714007 | 0.77 | NR1H4 (0.57) | PLK1MEN1RAB9AKMT2ANPC1 | |
| SCHEMBL9714011 | 0.77 | NR1H4 (0.57) | PLK1MEN1RAB9AKMT2ANPC1 | |
| SCHEMBL8740665 | 0.76 | MAPT (0.55) | MEN1KMT2ASMN1; SMN2MAPTLMNA | |
| SCHEMBL10749534 | 0.76 | KMT2A (0.45) | RAB9AKMT2ANPC1SMN1; SMN2MAPT | |
| SCHEMBL10749539 | 0.76 | KMT2A (0.45) | RAB9AKMT2ANPC1SMN1; SMN2MAPT | |
| SCHEMBL9713304 | 0.75 | PLK1 (0.53) | PLK1MEN1RAB9AKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5140046-A | Slow reacting substance of anaphylaxis antagonists | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-08-18 | — | — | US | disclosed |
| US-5116853-A | SRS-Antagonist, Antiallergens | MASE TOSHIYASU (JP) | 1992-05-26 | — | — | US | disclosed |
| EP-0218728-A1 | PHENYLENE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1987-04-22 | — | — | EP | disclosed |
| WO-1986005779-A1 | PHENYLENE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1986-10-09 | — | — | WO | disclosed |