⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2376484 | 0.97 | TSHR (0.35) | — | |
| SCHEMBL461606 | 0.90 | — | — | |
| Hydrogen Sulfide SCHEMBL22150853 | 0.88 | — | — | |
| SCHEMBL28788275 | 0.88 | — | — | |
| SCHEMBL826227 | 0.75 | — | — | |
| SCHEMBL12931405 | 0.71 | — | — | |
| SCHEMBL21270150 | 0.69 | TSHR (0.44) | — | |
| SCHEMBL15865292 | 0.69 | — | — | |
| SCHEMBL6715275 | 0.69 | — | — | |
| SCHEMBL30130597 | 0.67 | MAPK1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 218 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4695249-A1 | PHARMACEUTICAL FORMS OF QUINAZOLINE ERBB INHIBITORS | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2026-02-18 | — | — | EP | claimed |
| US-20250376808-A1 | BIODEGRADABLE BARRIER COATING | TERRAM TECH INC (US) | 2025-12-11 | — | — | US | claimed |
| EP-4632771-A1 | A METHOD FOR RAPID SINTERING OF RARE-EARTH MAGNET POWDERS BASED ON THERMAL RADIATION AND/OR CONVECTION | Jozef Stefan Institute (SI) | 2025-10-15 | — | — | EP | claimed |
| EP-4612153-A1 | PREPARATION OF PYRAZOLOPYRIDINE AND TRIAZOLOPYRIDINE DERIVATIVES AS NOVEL DIACYLGLYCERIDE O-ACYLTRANSFERASE 2 INHIBITORS | Merck Sharp & Dohme LLC (US) | 2025-09-10 | — | — | EP | claimed |
| US-20250223185-A1 | PROCESS FOR OBTAINING RE OXIDES | HyProMag GmbH (DE) | 2025-07-10 | — | — | US | claimed |
| EP-4499883-A1 | PROCESS FOR OBTAINING SE OXIDES | Hypromag GmbH (DE) | 2025-02-05 | — | — | EP | claimed |
| WO-2024213045-A1 | PHARMACEUTICAL FORMS OF QUINAZOLINE ERBB INHIBITORS | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2024-10-17 | — | — | WO | claimed |
| WO-2024097576-A1 | PREPARATION OF PYRAZOLOPYRIDINE AND TRIAZOLOPYRIDINE DERIVATIVES AS NOVEL DIACYLGLYCERIDE O-ACYLTRANSFERASE 2 INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2024-05-10 | — | — | WO | claimed |
| EP-4328219-A1 | SOS1 DEGRADING AGENT AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shanghai Leadingtac Pharmaceutical Co. Ltd. (CN) | 2024-02-28 | — | — | EP | claimed |
| CN-117499925-A | High-precision map drawing-oriented safety traceable data transmission method | 北京理工大学 | 2024-02-02 | — | — | CN | claimed |
| CN-115536660-A | Benzylamino-substituted heteropolycyclic compounds, compositions, formulations and uses thereof | 北京福元医药股份有限公司 | 2022-12-30 | — | — | CN | claimed |
| US-11369543-B2 | Non-visual precision spatial awareness device | Gamerman, Noah E (US) | 2022-06-28 | — | — | US | claimed |
| CN-114573514-A | Bridged bis-benzimidazole salt and preparation method and application thereof | 西安交通大学 | 2022-06-03 | — | — | CN | claimed |
| EP-1730152-B1 | TETRAHYDROQUINOLINE DERIVATIVES AND A PROCESS FOR PREPARING THE SAME | MITSUBISHI TANABE PHARMA CORP (JP) | 2012-05-02 | — | — | EP | claimed |
| US-20110039828-A1 | TETRAHYDROQUINOLINE DERIVATIVES AND A PROCESS FOR PREPARING THE SAME | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-02-17 | — | — | US | claimed |
| US-7781443-B2 | cholesteryl ester transfer protein (CETP) anatgonists such as 2R,4S)-4-{[3,5-Bis(trifluoromethyl)benzyl]-[5-(morpholin-4-yl)pyrimidin-2-yl]}amino-2-ethyl-6-methoxy-3,4-dihydro-2H-[1,5]naphthyridine-1-carboxylic acid ethyl ester, having improved bioavailability | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2010-08-24 | — | — | US | claimed |
| US-20070082896-A1 | Tetrahydroquinoline derivatives and a process for preparing the same | TANABE SEIYAKU CO., LTD. | 2007-04-12 | — | — | US | claimed |
| US-20070032485-A1 | Tetrahydronaphthyridine derivatives and a process for preparing the same | TANABE SEIYAKU CO., LTD. | 2007-02-08 | — | — | US | claimed |
| EP-1732924-A2 | TETRAHYDRONAPHTHYRIDINE DERIVATIVES AS CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS | TANABE SEIYAKU CO., LTD. (JP) | 2006-12-20 | — | — | EP | claimed |
| WO-2005095395-A2 | TETRAHYDRONAPHTHYRIDINE DERIVATIVES AS CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS | TANABE SEIYAKU CO., LTD. (JP) | 2005-10-13 | — | — | WO | claimed |