Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.78 |
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714492 | 0.92 | ABCB1 (0.78) | ABCB1POLBCYP3A4CYP2C9 | |
| SCHEMBL9714425 | 0.89 | ABCB1 (0.74) | ABCB1 | |
| SCHEMBL9714466 | 0.89 | ABCB1 (0.70) | ABCB1POLB | |
| SCHEMBL8178782 | 0.89 | POLB (0.65) | ABCB1POLBCYP3A4CYP2C9 | |
| SCHEMBL9714217 | 0.88 | POLB (0.72) | ABCB1POLBCYP3A4CYP2C9 | |
| SCHEMBL10721596 | 0.88 | POLB (0.63) | ABCB1POLBCYP3A4CYP2C9 | |
| SCHEMBL10721527 | 0.86 | POLB (0.60) | ABCB1POLBCYP3A4CYP2C9 | |
| Rh-5849 SCHEMBL1538531 | 0.84 | POLB (1.00) | ABCB1POLBCYP3A4CYP2C9 | |
| SCHEMBL9714085 | 0.84 | POLB (0.70) | ABCB1POLB | |
| SCHEMBL9714356 | 0.84 | POLB (0.70) | ABCB1POLBCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985461-A | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1991-01-15 | — | — | US | claimed |
| EP-0245950-B1 | INSECTICIDAL N-SUBSTITUTED-N' - SUBSTITUTED-N, N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1992-06-17 | — | — | EP | disclosed |
| EP-0236618-B1 | INSECTICIDAL N'-SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |
| US-4985461-A | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1991-01-15 | — | — | US | disclosed |
| EP-0236618-A2 | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |