SCHEMBL9714331

SCHEMBL9714331

CC(C)(C)N(NC(=O)c1ccc(Cl)cc1)C(=O)c1cccc(Cl)c1

nearest known ligand 0.78

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.70
CYP2C9 P11712 1/20 0.70
ABCB1 P08183 3/20 0.67
POLB P06746 1/20 0.62
HPGD P15428 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8178503 0.99 CYP3A4 (0.68) CYP3A4CYP2C9ABCB1POLBHPGD
SCHEMBL9714328 0.95 ABCB1 (0.71) CYP3A4CYP2C9ABCB1POLBHPGD
SCHEMBL9714363 0.93 CYP3A4 (0.81) CYP3A4CYP2C9ABCB1POLB
SCHEMBL9714349 0.93 ABCB1 (0.76) CYP3A4CYP2C9ABCB1POLB
SCHEMBL9714188 0.92 CYP3A4 (0.67) CYP3A4CYP2C9ABCB1POLB
Hydrochloric Acid SCHEMBL8179456 0.91 CYP3A4 (0.65) CYP3A4CYP2C9ABCB1POLB
SCHEMBL9714518 0.90 ABCB1 (0.72) CYP3A4CYP2C9ABCB1POLB
Hydrochloric Acid SCHEMBL8174695 0.88 ABCB1 (0.70) CYP3A4CYP2C9ABCB1POLB
SCHEMBL9714359 0.88 ABCB1 (0.77) CYP3A4CYP2C9ABCB1POLB
Halofenozide SCHEMBL55120 0.87 POLB (0.82) CYP3A4CYP2C9POLBHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4985461-A Insecticidal N'-substituted-N,N'-diacylhydrazines ROHM AND HAAS COMPANY (US) 1991-01-15 US claimed
EP-0245950-B1 INSECTICIDAL N-SUBSTITUTED-N' - SUBSTITUTED-N, N'-DIACYLHYDRAZINES ROHM AND HAAS COMPANY (US) 1992-06-17 EP disclosed
EP-0236618-B1 INSECTICIDAL N'-SUBSTITUTED-N,N'-DIACYLHYDRAZINES ROHM AND HAAS COMPANY (US) 1991-02-27 EP disclosed
US-4985461-A Insecticidal N'-substituted-N,N'-diacylhydrazines ROHM AND HAAS COMPANY (US) 1991-01-15 US disclosed
EP-0236618-A2 Insecticidal N'-substituted-N,N'-diacylhydrazines ROHM AND HAAS COMPANY (US) 1987-09-16 EP disclosed