SCHEMBL9714429

SCHEMBL9714429

NC(O)=S.OC(=S)Nc1ccc[nH]1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
TAS2R38 P59533 2/20 0.38
HSD17B10 Q99714 2/20 0.38
CYP1A2 P05177 1/20 0.38
TP53 P04637 1/20 0.38
TYR P14679 1/20 0.38
TSHR P16473 1/20 0.38
MAPK1 P28482 1/20 0.35
GAA P10253 3/20 0.33
MAPT P10636 2/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
KDM4E B2RXH2 1/20 0.33
CYP3A4 P08684 1/20 0.31
TYK2 P29597 1/20 0.31
GRIN2D O15399 1/20 0.31
GRIN3B O60391 1/20 0.31
GRIN1 Q05586 1/20 0.31
GRIN2A Q12879 1/20 0.31
GRIN2B Q13224 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6517811 0.98 CYP1A2 (0.37) ALDH1A1TAS2R38HSD17B10CYP1A2TP53
SCHEMBL3062314 0.94
SCHEMBL4502786 0.83
SCHEMBL3073349 0.75
SCHEMBL11115402 0.75
SCHEMBL29084179 0.75
SCHEMBL10610507 0.75
SCHEMBL3477030 0.75
SCHEMBL4502784 0.75
SCHEMBL14976786 0.74 NPC1 (0.46) ALDH1A1TAS2R38HSD17B10CYP1A2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992010214-A1 METHOD OF RADIOACTIVE LABELLING OF BLOOD CELLS AND KIT THEREFOR MALLINCKRODT MEDICAL, INC. (US) 1992-06-25 WO disclosed