Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8179823 | 0.99 | ABCB1 (0.60) | ABCB1CYP3A4POLBCYP2C9HPGD | |
| SCHEMBL9714472 | 0.94 | POLB (0.56) | ABCB1CYP3A4POLBCYP2C9HPGD | |
| SCHEMBL9714125 | 0.92 | POLB (0.59) | ABCB1CYP3A4POLBCYP2C9HPGD | |
| Hydrochloric Acid SCHEMBL8173165 | 0.90 | POLB (0.57) | ABCB1CYP3A4POLBCYP2C9HPGD | |
| SCHEMBL9498532 | 0.89 | POLB (0.63) | ABCB1CYP3A4POLBCYP2C9HPGD | |
| SCHEMBL9714093 | 0.89 | POLB (0.63) | ABCB1CYP3A4POLBCYP2C9HPGD | |
| SCHEMBL9714188 | 0.88 | CYP3A4 (0.67) | ABCB1CYP3A4POLBCYP2C9 | |
| SCHEMBL5053784 | 0.88 | POLB (0.55) | ABCB1CYP3A4POLBCYP2C9HPGD | |
| SCHEMBL9714469 | 0.88 | POLB (0.55) | ABCB1CYP3A4POLBCYP2C9HPGD | |
| Hydrochloric Acid SCHEMBL8166300 | 0.87 | POLB (0.61) | ABCB1CYP3A4POLBCYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0245950-B1 | INSECTICIDAL N-SUBSTITUTED-N' - SUBSTITUTED-N, N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1992-06-17 | — | — | EP | disclosed |
| EP-0236618-B1 | INSECTICIDAL N'-SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |
| US-4985461-A | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1991-01-15 | — | — | US | disclosed |
| EP-0236618-A2 | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |