Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10721281 | 0.88 | ABCB1 (0.71) | ABCB1HPGDSMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL10722318 | 0.83 | MEN1 (0.47) | ABCB1CYP3A4CYP2C9MEN1LMNA | |
| SCHEMBL9714478 | 0.82 | ABCB1 (0.56) | ABCB1HPGDSMN1; SMN2CYP3A4GAA | |
| SCHEMBL9557692 | 0.77 | TSHR (0.43) | ABCB1SMN1; SMN2LMNAMAPTKMT2A | |
| SCHEMBL9558002 | 0.76 | TSHR (0.44) | ABCB1SMN1; SMN2MAPTKMT2AFAAH | |
| SCHEMBL9714257 | 0.76 | CYP3A4 (0.60) | ABCB1HPGDSMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL9714435 | 0.75 | ABCB1 (0.72) | ABCB1HPGDSMN1; SMN2CYP3A4GAA | |
| SCHEMBL9714441 | 0.75 | ABCB1 (0.72) | ABCB1HPGDSMN1; SMN2CYP3A4GAA | |
| SCHEMBL9714325 | 0.73 | CYP3A4 (0.59) | ABCB1HPGDSMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL10721198 | 0.73 | SMN1; SMN2 (0.55) | ABCB1HPGDSMN1; SMN2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0245950-B1 | INSECTICIDAL N-SUBSTITUTED-N' - SUBSTITUTED-N, N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1992-06-17 | — | — | EP | disclosed |
| US-4985461-A | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1991-01-15 | — | — | US | disclosed |
| EP-0236618-A2 | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |