Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.38 |
| ▸ | PPARG | P37231 | 7/20 | 0.38 |
| ▸ | PPARD | Q03181 | 7/20 | 0.38 |
| ▸ | PPARA | Q07869 | 7/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.38 |
| ▸ | TLR2 | O60603 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | FABP4 | P15090 | 2/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11531287 | 0.98 | FFAR4 (0.45) | FFAR4FFAR1ALDH1A1GPR84PPARG | |
| SCHEMBL28791842 | 0.79 | FFAR4 (0.44) | FFAR4FFAR1ALDH1A1AKR1B1GPR84 | |
| SCHEMBL27998376 | 0.78 | FFAR4 (0.47) | FFAR4FFAR1ALDH1A1AKR1B1GPR84 | |
| SCHEMBL1199198 | 0.78 | FFAR4 (0.47) | FFAR4FFAR1ALDH1A1AKR1B1GPR84 | |
| SCHEMBL9487543 | 0.77 | FFAR4 (0.50) | FFAR4FFAR1ALDH1A1AKR1B1GPR84 | |
| SCHEMBL27998520 | 0.77 | FFAR4 (0.46) | FFAR4FFAR1ALDH1A1GPR84PPARG | |
| SCHEMBL9486689 | 0.76 | FFAR4 (0.44) | FFAR4FFAR1ALDH1A1AKR1B1GPR84 | |
| SCHEMBL28816528 | 0.76 | FFAR4 (0.49) | FFAR4FFAR1ALDH1A1AKR1B1GPR84 | |
| SCHEMBL9487075 | 0.76 | FFAR4 (0.44) | FFAR4FFAR1ALDH1A1AKR1B1GPR84 | |
| SCHEMBL9486548 | 0.76 | FFAR4 (0.44) | FFAR4FFAR1ALDH1A1AKR1B1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166369-A | Precursors and synthesis of D1-(methyl)-16,16-(dimethyl)-11-alpha, 15-alpha, beta-dihydroxy-9-oxo-2,13,-trans, trans-prostadienoates | AMERICAN CYANAMID COMPANY | 1992-11-24 | — | — | US | disclosed |
| US-4983753-A | Precursors and synthesis of di-(methyl)-16,16-(dimethyl)-11-alpha,15-alpha beta-dihydroxy-9-oxo-2,13-trans,trans-prostadienoates | FLOYD JR MIDDLETON B (US) | 1991-01-08 | — | — | US | disclosed |
| EP-0065638-B1 | SUBSTITUTED 7-(4-SUBSTITUTED-CYCLOPENT-2-EN-1-ON-2-YL)-HEPT-2-TRANSENOATES | AMERICAN CYANAMID COMPANY (US) | 1989-01-25 | — | — | EP | disclosed |
| US-4644079-A | Precursors and synthesis of d1-(methyl)-16,16-(dimethyl)-11-alpha, 15-alpha, beta-dihydroxy-9-oxo-2,13,-trans, trans-prostadienoates | AMERICAN CYANAMID COMPANY (US) | 1987-02-17 | — | — | US | disclosed |
| US-4474979-A | Synthesis of d1-(methyl)-16,16-(dimethyl-11-alpha, 15-alpha, beta-dihydroxy-9-oxo-2,13,-trans,trans-prostadienoates | AMERICAN CYANAMID COMPANY (US) | 1984-10-02 | — | — | US | disclosed |
| US-4360688-A | Precursors and synthesis of d1-(methyl)-16,16-(dimethyl)-11-alpha, 15-alpha, beta-dihydroxy-9-oxo-2,13,-trans, trans-prostadienoates | AMERICAN CYANAMID COMPANY (US) | 1982-11-23 | — | — | US | disclosed |