Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 3/20 | 0.32 |
| ▸ | CNR2 | P34972 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9488229 | 0.82 | FEN1 (0.49) | FEN1CNR1CNR2 | |
| SCHEMBL9629791 | 0.81 | FEN1 (0.48) | FEN1CNR1CNR2 | |
| SCHEMBL10427749 | 0.77 | MEN1 (0.42) | FEN1CNR1CNR2 | |
| SCHEMBL10427743 | 0.77 | FEN1 (0.39) | FEN1 | |
| Water SCHEMBL9715629 | 0.76 | FEN1 (0.34) | FEN1CNR1CNR2 | |
| SCHEMBL9629023 | 0.73 | FEN1 (0.46) | FEN1CNR1CNR2 | |
| SCHEMBL10667466 | 0.71 | MAPT (0.45) | CNR1CNR2 | |
| SCHEMBL10582954 | 0.71 | FEN1 (0.44) | FEN1 | |
| SCHEMBL10580192 | 0.70 | FEN1 (0.36) | FEN1 | |
| SCHEMBL10427736 | 0.69 | FEN1 (0.37) | FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232328-B1 | ZWITTERIONIC BICYCLIC COMPOUNDS AND THEIR SALTS, SOLVATES, HYDRATES AND ESTERS | SCHERING CORPORATION (US) | 1992-04-15 | — | — | EP | disclosed |
| US-4902693-A | Anti-allergic esters, acetal ethers, thioethers and nitrogen substituted derivatives of bicyclic compounds | SCHERING CORPORATION (US) | 1990-02-20 | — | — | US | disclosed |
| EP-0302303-A2 | Bicyclic compounds, their use as pharmaceuticals, their preparation, and intermediates useful in their preparation | SCHERING CORPORATION (US) | 1989-02-08 | — | — | EP | disclosed |
| US-4794116-A | ANTIINFLAMMATORY AGENTS, CYTOPROTECTIVE AGENTS IN TREATMENT OF HYPERPROLIFERATIVE SKIN DISEASE | SCHERING CORPORATION (US) | 1988-12-27 | — | — | US | disclosed |
| US-4782067-A | Anti-allergic composition containing zwitterionic bicyclic compounds | SCHERING CORPORATION (US) | 1988-11-01 | — | — | US | disclosed |
| EP-0232328-A1 | ZWITTERIONIC BICYCLIC COMPOUNDS AND THEIR SALTS, SOLVATES, HYDRATES AND ESTERS. | SCHERING CORP (US) | 1987-08-19 | — | — | EP | disclosed |
| US-4684727-A | Zwitterionic 1,8-naphthyridine and pyrazino[2,3-b]pyridine containing compounds useful as anti-allergic, anti-inflammatory and cycloprotective agents | SCHERING CORPORATION (US) | 1987-08-04 | — | — | US | disclosed |
| WO-1987000752-A2 | ZWITTERIONIC BICYCLIC COMPOUNDS AND THEIR SALTS, SOLVATES, HYDRATES AND ESTERS | SCHERING CORPORATION (US) | 1987-02-12 | — | — | WO | disclosed |