Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.31 |
| ▸ | PPM1B | O75688 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5954132 | 0.85 | NPSR1 (0.43) | HCAR2SMN1; SMN2GAALMNAALDH1A1 | |
| SCHEMBL9858359 | 0.80 | HCAR2 (0.38) | HCAR2SMN1; SMN2GAALMNAALDH1A1 | |
| SCHEMBL5282874 | 0.74 | HCAR2 (0.48) | HCAR2SMN1; SMN2GAALMNAALDH1A1 | |
| SCHEMBL2231356 | 0.74 | HCAR2 (0.48) | HCAR2SMN1; SMN2GAALMNAALDH1A1 | |
| SCHEMBL138475 | 0.72 | HCAR2 (0.48) | HCAR2SMN1; SMN2GAALMNAALDH1A1 | |
| Propene SCHEMBL4319122 | 0.72 | TSHR (0.45) | HCAR2SMN1; SMN2GAALMNAALDH1A1 | |
| SCHEMBL20262479 | 0.72 | HCAR2 (0.45) | HCAR2SMN1; SMN2GAALMNAALDH1A1 | |
| SCHEMBL27743388 | 0.71 | HCAR2 (0.45) | HCAR2SMN1; SMN2GAALMNAALDH1A1 | |
| SCHEMBL414106 | 0.71 | — | — | |
| SCHEMBL8622644 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1050763-C | Enhanced skin penetration system for improved topical delivery of drugs | RICHARDSON VICKS INC (US) | 2000-03-29 | — | — | CN | claimed |
| CN-1072602-A | Improve the enhanced dermal osmosis system of the local conveying of medicine | RICHARDSON VICKS INC (US) | 1993-06-02 | — | — | CN | claimed |
| CN-1244316-C | Absorbent article with barrier sheet to prevent migration of skin care composition | PROCTER & GAMBLE (US) | 2006-03-08 | — | — | CN | disclosed |
| CN-1380824-A | Absorbent article having barrier sheet against migration of skin care composition | PROCTER & GAMBLE (US) | 2002-11-20 | — | — | CN | disclosed |
| CN-1379688-A | Absorbent article with skin care composition | PROCTER & GAMBLE (US) | 2002-11-13 | — | — | CN | disclosed |
| CN-1079665-C | Personal cleansing compositions | PROCTER & GAMBLE (US) | 2002-02-27 | — | — | CN | disclosed |
| CN-1130864-A | Personal cleansing compositions | PROCTER & GAMBLE (US) | 1996-09-11 | — | — | CN | disclosed |
| EP-0298319-B1 | HOT MELT ADHESIVE COMPRISING WATER SOLUBLE POLYALKYLOXAZOLINE AND WATER INSOLUBLE POLYMER | H.B. FULLER LICENSING & FINANCING, INC. (US) | 1992-12-09 | — | — | EP | disclosed |
| US-5143961-A | Hot melt adhesive comprising water soluble polyalkyloxazoline and water insoluble polymer | H. B. FULLER LICENSING & FINANCING INC. (US) | 1992-09-01 | — | — | US | disclosed |
| US-4990339-A | Comprising polyoxazolines, hydroxy or carboxylic acid diluent, tackifier; wound healing, easy removal | H. B. FULLER COMPANY (US) | 1991-02-05 | — | — | US | disclosed |
| EP-0298319-A1 | Hot melt adhesive comprising water soluble polyalkyloxazoline and water insoluble polymer | H.B. FULLER LICENSING & FINANCING, INC. (US) | 1989-01-11 | — | — | EP | disclosed |
| EP-0297451-A1 | Hot melt adhesive comprising an N-substituted polyalkyleneimine and acid functional component | H.B. FULLER COMPANY (US) | 1989-01-04 | — | — | EP | disclosed |