SCHEMBL9715860

SCHEMBL9715860

O=C(O)c1ccc(C(=O)Oc2ccc(-c3ccc(O)cc3)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.61
CA1 P00915 2/20 0.57
CA2 P00918 2/20 0.57
CA12 O43570 1/20 0.57
CA3 P07451 1/20 0.57
TYR P14679 1/20 0.57
DRD1 P21728 1/20 0.57
CA4 P22748 1/20 0.57
CA6 P23280 1/20 0.57
CA5A P35218 1/20 0.57
CA7 P43166 1/20 0.57
CA9 Q16790 1/20 0.57
CA14 Q9ULX7 1/20 0.57
CA5B Q9Y2D0 1/20 0.57
SENP1 Q9P0U3 1/20 0.54
SRD5A2 P31213 1/20 0.52
PARP10 Q53GL7 1/20 0.50
LMNA P02545 2/20 0.47
KDM4E B2RXH2 1/20 0.47
EGFR P00533 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Paraben SCHEMBL5083113 1.00 HSD17B10 (0.61) HSD17B10CA1CA2CA12CA3
SCHEMBL5015778 1.00 HSD17B10 (0.61) HSD17B10CA1CA2CA12CA3
SCHEMBL10495256 1.00 HSD17B10 (0.61) HSD17B10CA1CA2CA12CA3
SCHEMBL14567082 1.00 HSD17B10 (0.61) HSD17B10CA1CA2CA12CA3
SCHEMBL10493933 1.00 HSD17B10 (0.61) HSD17B10CA1CA2CA12CA3
SCHEMBL8422974 0.94 CA1 (0.64) HSD17B10CA1CA2CA12CA3
SCHEMBL667872 0.94 CA1 (0.64) HSD17B10CA1CA2CA12CA3
SCHEMBL20500513 0.94 CA1 (0.64) HSD17B10CA1CA2CA12CA3
Paraben SCHEMBL5083082 0.94 CA1 (0.64) HSD17B10CA1CA2CA12CA3
SCHEMBL17734117 0.94 CA1 (0.64) HSD17B10CA1CA2CA12CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0427795-A4 HIGH STRENGTH POLYMERS AND BLENDS OF HYDROQUINONE POLY(ISO-TEREPHTHALATES) CONTAINING RESIDUES OF P-HYDROXYBENZOIC ACID 1992-11-25 EP disclosed
EP-0427795-A1 HIGH STRENGTH POLYMERS AND BLENDS OF HYDROQUINONE POLY(ISO-TEREPHTHALATES) CONTAINING RESIDUES OF p-HYDROXYBENZOIC ACID. AMOCO CORP (US) 1991-05-22 EP disclosed
US-4818807-A Liquid-crystalline polymer IDEMITSU KOSAN CO., LTD. (JP) 1989-04-04 US disclosed
EP-0258898-A2 Liquid-crystalline polymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1988-03-09 EP disclosed