Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 8/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 3/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10604578 | 0.87 | PLA2G10 (0.47) | TLR2PLA2G10PLA2G2APLA2G1BPLA2G5 | |
| SCHEMBL10604671 | 0.87 | PLA2G10 (0.47) | TLR2PLA2G10PLA2G2APLA2G1BPLA2G5 | |
| SCHEMBL10605748 | 0.87 | PLA2G10 (0.47) | TLR2PLA2G10PLA2G2APLA2G1BPLA2G5 | |
| SCHEMBL18641859 | 0.87 | PLA2G10 (0.47) | TLR2PLA2G10PLA2G2APLA2G1BPLA2G5 | |
| SCHEMBL18484325 | 0.85 | TLR2 (0.44) | TLR2PLA2G10PLA2G2APLA2G1BPLA2G5 | |
| SCHEMBL22268845 | 0.85 | TLR2 (0.44) | TLR2PLA2G10PLA2G2APLA2G1BPLA2G5 | |
| SCHEMBL6813695 | 0.85 | PLA2G10 (0.50) | TLR2PLA2G10PLA2G2APLA2G1BPLA2G5 | |
| SCHEMBL10563646 | 0.83 | PLA2G10 (0.44) | TLR2PLA2G10PLA2G2APLA2G1BPLA2G5 | |
| SCHEMBL25227181 | 0.82 | USP2 (0.47) | TLR2CETP | |
| SCHEMBL25227184 | 0.82 | USP2 (0.47) | TLR2CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5103007-A | Antitumor agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-04-07 | — | — | US | disclosed |
| EP-0378763-A1 | Lipids, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-07-25 | — | — | EP | disclosed |